No-Fuss Gluten-Free Meatloaf

Classic Meatloaf
Getty Images // Robert Reiff
    75 mins
Ratings (25)

Meatloaf is one of those ultimate no-fail comfort foods. Hearty and filling, simple to prepare, and loaded with flavor. Meatloaf was a staple in my house growing up, and with a few small changes, I can still enjoy meatloaf as a gluten-free adult. 

This no-fuss Gluten-Free Meatloaf recipe makes a big loaf, which means meatloaf leftovers. If you've never had a thick slab of leftover meatloaf between two pieces of gluten-free bread, you should try it with this recipe. The Ultimate Sandwich. 

To make meatloaf gluten-free, simply swap regular bread crumbs for gluten-free bread or cracker crumbs. Also, confirm the ketchup and Worcestershire sauce used in this recipe are ones that do not contain gluten.

Keep a batch or two of homemade gluten-free breadcrumbs in the freezer, and you'll be set to make gluten-free meatloaf anytime you want. Easy and convenient!

When purchasing sauces for this recipe, be sure to check labels as some brands include gluten. Annie's Naturals Organic Ketchup is a delicious gluten-free ketchup option and a staple in my fridge. 

To lighten up this recipe, swap ground turkey in place of ground beef. To add a little heat to your meatloaf, add a 1/4 tsp of red pepper flakes. 

Edited by Stephanie Kirkos, July 2016

What You'll Need

  • 2 pounds ground beef
  • 2 large eggs
  • 2 ounces applesauce
  • 1 cup gluten-free cracker crumbs or gluten-free bread crumbs
  • 1 medium chopped onion
  • 1/4 cup chopped green pepper
  • 2 teaspoons gluten-free Worcestershire sauce
  • 1 cup gluten-free ketchup - divided (I used Annie's Naturals Organic Ketchup)

How to Make It

  1. Preheat oven to 400° F / 204° C
  2. Combine all ingredients EXCEPT 1/2 cup of ketchup in a large mixing bowl.
  3. Use your hands to thoroughly blend the mixture. (I like to use disposable gloves for this job).
  4. Add a small amount of milk or water, if necessary, to moisten the mixture.
  5. Use a large spatula to scoop the meat mixture into a 9x5x3-inch loaf pan. Press down and smooth the top.
  6. Bake in preheated oven for 30 minutes. Carefully remove pan and pour off excess fat.
  1. Spread remaining 1/2 cup ketchup over the top of ​the loaf, return to oven and bake for an additional 30 minutes.

Reminder: Always make sure your work surfaces, utensils, pans, ​and tools are free of gluten. Always read product labels. Manufacturers can change product formulations without notice. When in doubt, do not buy or use a product before contacting the manufacturer for verification that the product is free of gluten.